ISSN 1308-7649 | E-ISSN 2148-3817
Original Article
Differences in Antibiotic Resistance of MRSA Infections in Patients with Various Types of Otitis Media
1 Department of Otorhinolaryngology, Head and Neck Surgery, Seoul National University School of Medicine, Seoul, Korea  
2 Department of Otorhinolaryngology, Head and Neck Surgery, Kyung Hee University, Seoul, Korea  
3 Department of Otorhinolaryngology, Head and Neck Surgery, Hallym University School of Medicine, Seoul, Korea  
4 Department of Otorhinolaryngology, Head and Neck Surgery, Yeungnam University School of Medicine, Daegu, Korea  
5 Department of Otorhinolaryngology, Head and Neck Surgery, Eulji University School of Medicine, Daejon, Korea  
6 Department of Otorhinolaryngology, Head and Neck Surgery, The Catholic University School of Medicine, Incheon, Korea  
7 Department of Otorhinolaryngology, Head and Neck Surgery, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Korea  
J Int Adv Otol ; : -
DOI: 10.5152/iao.2018.5374
Key Words: Methicillin resistance, Staphylococcus aureus, chronic suppurative otitis media, cholesteatoma, otitis media with effusion, acute otitis media
Abstract

 

OBJECTIVES: We investigated the epidemiological and antibiotic resistance differences in methicillin-resistant Staphylococcus aureus (MRSA) infections in patients with otitis media with effusion (OME), acute otitis media (AOM), chronic suppurative otitis media (CSOM), and chronic cholesteatomatous otitis media (CCOM).

 

MATERIALS and METHODS: We conducted a retrospective study of patients with newly identified MRSA infections from January 2009 through January 2017. Overall, 3,522 patients from 10 tertiary referral hospitals were included in the study. An antibiotic sensitivity test was performed for each isolate.

 

RESULTS: MRSA infections in patients with CSOM and CCOM were more resistant to ciprofloxacin, clindamycin, erythromycin, gentamicin, levofloxacin, and tetracycline. Patients showed good susceptibility to rifampicin, trimethoprim/sulfamethoxazole (TMP/SMX), and vancomycin.

 

CONCLUSION: MRSA infections in various otitis media cases showed different resistance patterns. MRSA infections in patients with COM and CCOM were more resistant to antibiotics than those in patients with OME and AOM.

 

Cite this article as: Park MK, Nam DW, Byun JY, Hong SM, Bae CH, Lee HY, et al. Differences in Antibiotic Resistance of MRSA Infections in Patients with Various Types of Otitis Media. J Int Adv Otol 2018. DOI: 10.5152/iao.2018.5374.

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