The Journal of International
Advanced Otology
Original Article

Cochlear Implant Electrode Array From Partial to Full Insertion in Non-Human Primate Model


Department of Otorhinolaryngology, University of Navarra Clinic, Pamplona/Navarra, Spain

J Int Adv Otol 2018; 14: 5-9
DOI: 10.5152/iao.2018.5233
Read: 2909 Downloads: 861 Published: 03 September 2019


OBJECTIVES: To determine the feasibility of progressive insertion (two sequential surgeries: partial to full insertion) of an electrode array and to compare functional outcomes.


MATERIAL and METHODS: 8 normal-hearing animals (Macaca fascicularis (MF)) were included. A 14 contact electrode array, which is suitably sized for the MF cochlea was partially inserted (PI) in 16 ears. After 3 months of follow-up revision surgery the electrode was advanced to a full insertion (FI) in 8 ears. Radiological examination and auditory testing was performed monthly for 6 months. In order to compare the values a two way repeated measures ANOVA was used. A p-value below 0.05 was considered as statistically significant. IBM SPSS Statistics V20 was used.


RESULTS: Surgical procedure was completed in all cases with no complications. Mean auditory threshold shift (ABR click tones) after 6 months follow-up is 19 dB and 27 dB for PI and FI group. For frequencies 4, 6, 8, 12, and 16 kHz in the FI group, tone burst auditory thresholds increased after the revision surgery showing no recovery thereafter. Mean threshold shift at 6 months of follow- up is 19.8 dB ranging from 2 to 36dB for PI group and 33.14dB ranging from 8 to 48dB for FI group. Statistical analysis yields no significant differences between groups.


CONCLUSION: It is feasible to perform a partial insertion of an electrode array and progress on a second surgical time to a full insertion (up to 270º). Hearing preservation is feasible for both procedures. Note that a minimal threshold deterioration is depicted among full insertion group, especially among high frequencies, with no statistical differences.


Cite this article as: Manrique-Huarte R, Calavia D, Gallego MA, Manrique M. Cochlear implant electrode array from partial to full insertion in non-human primate model. J Int Adv Otol 2018; 14(1): 5-9.

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