The Journal of International
Advanced Otology
Case Report

Repeated Attacks of Dizziness Caused by a Rare Mitochondrial Encephalomyopathy


Department of Otolaryngology-Head and Neck Surgery, Nihon University School of Medicine, Tokyo, Japan


Department of Neurology, National Hospital Organization Saitama National Hospital, Saitama, Japan


Department of Medicine, Division of Neurology, Nihon University School of Medicine, Tokyo, Japan


Department of Otolaryngology, Tokyo Women’s Medical University Medical Center East, Tokyo, Japan

J Int Adv Otol 2018; 14: 157-160
DOI: 10.5152/iao.2018.4467
Read: 1973 Downloads: 470 Published: 03 September 2019


Cases of dizziness caused by multiple sclerosis are commonly reported, but those caused by mitochondrial encephalomyopathy have been rarely reported. Particularly, the description of eye nystagmography (ENG) using caloric and optokinetic nystagmus tests has not been reported to date. We encountered the case of a 40-year-old woman with mitochondrial encephalomyopathy who visited us with the chief complaint of dizziness. At first, we considered multiple sclerosis based on the magnetic resonance imaging (MRI) findings and dizziness. Repeated attacks of dizziness and serum lactic acid levels suggested mitochondrial encephalomyopathy. A muscle biopsy confirmed the diagnosis. ENG findings suggested central vestibular disorder of the cerebellum and brainstem. This case suggests that we should not rule out the differential diagnosis of a very rare mitochondrial encephalomyopathy in patients who experience dizziness with MRI findings indicative of multiple sclerosis.


Cite this article as: Toi T, Nomura Y, Kishino A, Shigihara S, Oshima T, Ishikawa H, et al. Repeated Attacks of Dizziness Caused bya Rare Mitochondrial Encephalomyopathy. J Int Adv Otol 2018; 14(1): 157-60.

EISSN 2148-3817