The Journal of International
Advanced Otology

Spiral Ganglions and Speech Perception in the Elderly. Which Turn of the Cochlea is the More Relevant? A Preliminary Study on Human Temporal Bones

1.

Department of Otolaryngology, University of Perugia, Perugia, Italy

2.

Otology and Cochlear Implant Unit, Regional Referral Centre Children's Hospital "Santobono-Pausilipon", Naples, Italy

3.

Department of Organ of Sense, University La Sapienza, Rome, Italy

4.

Department of Otolaryngology, Santobono Posilipon Hospital, Naples, Italy

5.

Department of Otolaryngology, University of Perugia, Perugia, Italy

J Int Adv Otol 2020; 16: 318-322
DOI: 10.5152/iao.2020.8481
Read: 15 Downloads: 14 Published: 16 October 2020

OBJECTIVES: To identify the cochlear segment in which spiral ganglion neuron (SGN) loss may more severely impact discrimination thresholds.

MATERIALS and METHODS: Thirteen temporal bones from 13 subjects between 55 and 77 years of age were analyzed. The organ of corti was analyzed to identify the loss of hair cells, and the number of SGNs in each cochlear segment were counted. The results of the speech perception test (SPT) and pure tone audiometry (PTA) tests were collected. PTA averages for low and high frequencies were calculated. One-way analysis of variance (ANOVA), Pearson, Spearman, and multilinear regression tests were performed.

RESULTS: No statistically significant correlation was identified between the patient’s age and number of SGNs. Statistically significant differences were observed between the number of SGNs in the different cochlear segments (one-way ANOVA: p<0.0001) and between poor PTA average and SPT scores (negative correlation) (p=0.03). A statistically significant correlation was identified between the overall number of cochlear SGNs and SPT scores (p=0.02) and between the number of SGNs in cochlear segments I (p=0.04) and II and the SPT score (p=0.03).

CONCLUSIONS: We identified that residual SGNs in the basal and middle turns of the cochlea might be determinants of speech perception.

Cite this article as: van Di Stadio A, della Volpe A, Ralli M, Korsch F, Greco A, Ricci G. Spiral Ganglions and Speech Perception in the Elderly. Which Turn of the Cochlea is the More Relevant? A Preliminary Study on Human Temporal Bones. J Int Adv Otol 2020; 16(3): 318-22.

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ISSN1308-7649 EISSN 2148-3817