The Journal of International Advanced Otology
Original Article

E-ABR in Patients with Cochlear Implant: A Comparison between Patients with Malformed Cochlea and Normal Cochlea


Department of Otolaryngology, University of Perugia, Perugia, Italy


Highland Instrument, Engineer, Cambridge, USA


Cochlear Implant Unit, Santobono Hospital, Naples, Italy


Department Of Otolaryngology, Meyer University Hospital, Florence, Italy


Department Of Otolaryngology, University of Palermo, Palermo, Italy

J Int Adv Otol 2019; 15: 215-221
DOI: 10.5152/iao.2019.6251
Read: 129 Downloads: 144 Published: 03 September 2019



OBJECTIVES: This study aims to compare the electrical auditory brainstem response (EABR) following cochlear implant (CI) surgery in pediatric subjects with cochlear malformation and a normal cochlea, in order to assess the sensitivity of EABR and to evaluate the surgery outcome.


MATERIALS and METHODS: A total of 26 pediatric subjects who were deaf and scheduled for CI surgery were enrolled into this case control study. Group A (n=20) included subjects with a normo-conformed cochlea. Group B (n=6) included subjects with cochlear malformation. Subjects were evaluated with EABR immediately (T0) and 6 months (T1) post-CI surgery. The EABR Waves III and V average amplitude and latency were compared across time, separately for each group, and across groups, separately for each time.


RESULTS: Auditory brainstem response (ABR) could only be recorded in Group A. We were able to record EABR from all subjects at T0 and T1, and waves III and V were present in all the recorded signals. There were no statistically significant differences between T0 and T1 in EABR Waves III and V in terms of average amplitude and latency in neither group. When comparing Groups A and B, the only statistically significant difference was the average amplitude of wave V, both at T0 and T1.


CONCLUSION: EABR is a valid tool to measure the auditory nerve integrity after CI surgery in patients with a normal and malformed cochlea, as shown by its ability to measure waves III and V when ABR is absent. The EABR testing should be performed before and after CI surgery, and EABR should be used as a measure of outcome, especially in patients with a malformed cochlea.


Cite this article as: Di Stadio A, Dipietro L, De Lucia A, Trabalzini F, Ricci G, Martines F, et al. E-ABR in Patients with Cochlear Implant: A Comparison between Patients with Malformed Cochlea and Normal Cochlea. J Int Adv Otol 2019; 15(2): 215-21.

ISSN1308-7649 EISSN 2148-3817